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Niels C Riedemann Selected Research

vilobelimab

1/2022The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19.
12/2020Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial.

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Niels C Riedemann Research Topics

Disease

28Sepsis (Septicemia)
04/2015 - 06/2002
5Infections
01/2022 - 10/2012
3Septic Shock (Toxic Shock Syndrome)
08/2014 - 01/2012
3Acute Lung Injury
03/2005 - 07/2002
2COVID-19
01/2022 - 12/2020
2Pneumonia (Pneumonitis)
01/2022 - 12/2020
2Inflammation (Inflammations)
12/2020 - 07/2002
2Lung Injury
02/2015 - 03/2005
1Dyspnea (Shortness of Breath)
12/2020
1Glomerulonephritis
01/2017
1Atypical Hemolytic Uremic Syndrome
01/2017
1Death (Near-Death Experience)
04/2015
1Viral Pneumonia
02/2015
1Wounds and Injuries (Trauma)
10/2012
1Hemorrhage
10/2012
1Pneumococcal Pneumonia
10/2012
1Liver Diseases (Liver Disease)
01/2012
1Peritonitis
01/2012
1Cholestasis
01/2012
1Critical Illness (Critically Ill)
01/2012
1Acute Kidney Injury (Acute Renal Failure)
06/2011
1Pulmonary Edema
03/2005
1Reperfusion Injury
02/2003

Drug/Important Bio-Agent (IBA)

7Complement System Proteins (Complement)IBA
12/2020 - 01/2003
6Anaphylatoxin C5a ReceptorIBA
02/2004 - 06/2002
4CytokinesIBA
03/2011 - 01/2003
4Interleukin-6 (Interleukin 6)IBA
05/2007 - 01/2003
3AnaphylatoxinsIBA
01/2022 - 02/2015
3Immunoglobulin G (IgG)IBA
06/2005 - 07/2002
3Proteins (Proteins, Gene)FDA Link
03/2005 - 07/2002
3Messenger RNA (mRNA)IBA
04/2004 - 07/2002
2Monoclonal AntibodiesIBA
01/2022 - 12/2020
2vilobelimabIBA
01/2022 - 12/2020
2Antigen-Antibody Complex (Immune Complex)IBA
03/2005 - 07/2002
1EnzymesIBA
01/2022
1Oxygen (Dioxygen)IBA
12/2020
1eculizumabFDA Link
01/2017
1VancomycinFDA LinkGeneric
08/2014
1Biomarkers (Surrogate Marker)IBA
10/2012
1ProcalcitoninIBA
10/2012
1p38 Mitogen-Activated Protein KinasesIBA
10/2012
14-O-carboxymethylascochlorinIBA
01/2012
1Taurodeoxycholic AcidIBA
01/2012
1Chenodeoxycholic Acid (Chenix)FDA Link
01/2012
1BilirubinIBA
01/2012
1Bile Acids and Salts (Bile Acids)IBA
01/2012
1AnionsIBA
01/2012
1Neutralizing AntibodiesIBA
01/2012
1GelatinIBA
06/2011
1Hydroxyethyl Starch Derivatives (Pentastarch)FDA Link
06/2011
1Starch (Cornstarch)IBA
06/2011
1Colloids (Colloid)IBA
06/2011
1Complement C1q (C1q Complement)IBA
03/2011
1Complement C5a (Complement 5a)IBA
10/2010
1Interleukin-8 (Interleukin 8)IBA
10/2010
1Interleukin-10 (Interleukin 10)IBA
05/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2007
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
05/2007
1CXC ChemokinesIBA
07/2006
1AntibodiesIBA
06/2005
1AlbuminsIBA
03/2005
1Peroxidase (Myeloperoxidase)IBA
03/2005
1Macrophage Migration-Inhibitory FactorsIBA
07/2004
1Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
04/2004
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
04/2004
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2003
1LipopolysaccharidesIBA
12/2003
1LigandsIBA
10/2003
1NF-kappa B (NF-kB)IBA
08/2003
1Pharmaceutical PreparationsIBA
05/2003
1Protein CIBA
04/2003
1LipidsIBA
10/2002
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
07/2002
1IntegrinsIBA
07/2002
1CaspasesIBA
06/2002
1Annexin A5IBA
06/2002

Therapy/Procedure

14Punctures
01/2012 - 06/2002
14Ligation
01/2012 - 06/2002
5Therapeutics
04/2015 - 08/2003
1Terminal Care (Care, Terminal)
04/2015
1Renal Replacement Therapy (Therapies, Renal Replacement)
08/2014
1Laparotomy
10/2012
1Drug Therapy (Chemotherapy)
01/2012
1Resuscitation
06/2011
1Fluid Therapy (Oral Rehydration Therapy)
06/2011